FIGURE 5.

Risk models are associated with genomic instability (A) Comparing low and high risk group tumor sectors (top), bar chart showing the altered genome fraction (second top), heatmap showing differential copy number variations (CNV) level (middle) and copy number status of the selected genes showing significant deletion or amplification (bottom). (B) Waterfall plot of the top 20 mutant genes in the high and low risk groups (B-1: high risk group, B-2: low risk group). (C) Wordclouds were drawn with size of scripts bound up with amounts of samples containing certain mutant genes in the high and low risk groups (C-1: high risk group, C-2: low risk group). (D) Correlation heat map to show the degree of correlation between mutant genes in the high and low risk groups (D-1: high risk group, D-2: low risk group). (E) Volcano map used to demonstrate mutation driver genes in the high and low risk groups (E−1: high risk group, E−2: low risk group).