Low-molecular-weight DNA electrophoresed on a 10% polyacrylamide gel after treatment with different enzymes. Lane 1, a 20-bp ladder used as a molecular size standard; lane 2, untreated control DNA; lane 3, DNA treated with RNase H; lane 4, heat-treated DNA; lane 5, DNA treated with RNase A; lane 6, DNA treated with DNase I; lane 7, DNA treated with S1 nuclease.