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Quantitative scoring of histopathological examination of heart tissues using H & E staining
| Groups | Scoring for intermuscular edema (Mean ± SD) | Scoring for cardiomyocytes degeneration (Mean ± SD) |
|---|---|---|
| Normal control | 0.00 ± 0.00 | 0.00 ± 0.00 |
| Doxorubicin control | 2.33 ± 0.51***a | 2.16 ± 0.40***a |
| Doxorubicin + MET 250 mg/kg | 1.50 ± 0.54*b | 1.16 ± 0.40***b |
| Doxorubicin + MET 180 mg/kg | 1.33 ± 0.51**b | 1.33 ± 0.51**b |
| Doxorubicin + DAPA 0.9 mg/kg | 1.16 ± 0.40***b | 1.16 ± 0.40***b |
