Table 9.
Sensitivity to change
| Baseline | WEEK 24 | Mean difference | Effect sizea | |||||
|---|---|---|---|---|---|---|---|---|
| N | Mean | SD | N | Mean | SD | |||
| Injection difficulties (3 items) | 59 | 27.1 | 28.5 | 59 | 14.1 | 23.2 | – 13.0 | – 0.46 |
| Physical impact (6 items) | 59 | 21.6 | 20.7 | 59 | 15.5 | 19.1 | – 6.1 | – 0.30 |
| Treatment bother (7 items) | 59 | 22.3 | 19.0 | 59 | 10.7 | 14.6 | – 11.7 | – 0.62 |
| Interference (4 items) | 59 | 23.0 | 20.0 | 59 | 9.0 | 16.9 | – 14.0 | – 0.70 |
| Emotional impact (6 items) | 59 | 22.5 | 18.4 | 59 | 12.1 | 14.7 | – 10.4 | – 0.56 |
| Total score | 59 | 23.3 | 16.8 | 59 | 12.3 | 15.6 | – 11.0 | – 0.66 |
aEffect size: mean change score divided by the standard deviation of the baseline score