Table II.
Univariate and multivariate analysis of clinicopathological factors to predict relapse-free survival.
| Multivariate analysis | ||||
|---|---|---|---|---|
|
|
||||
| Variable | Univariate P-valuea | HRb | 95% CIc | P-valued |
| Sex | ||||
| Male | 0.42 | |||
| Female | ||||
| Age, years | ||||
| <65 | 0.27 | |||
| ≧65 | ||||
| Tumor depth | ||||
| pT3pT4 | <0.01 | 4.59 | 1.36-15.57 | 0.01 |
| pT1pT2 | ||||
| Nodal status | ||||
| Positive | <0.01 | 3.30 | 1.67-6.52 | <0.01 |
| Negative | ||||
| JMJD6-Abs | ||||
| ≥5,720 | 0.02 | 2.39 | 1.28-4.46 | <0.01 |
| <5,720 | ||||
| Distant metastasis | ||||
| Positive | <0.01 | 3.29 | 1.52-7.14 | <0.01 |
| Negative | ||||
| Histology | ||||
| Muc, Poor | 0.36 | |||
| Tub | ||||
| CEA | ||||
| Positive | 0.32 | 0.71 | 0.36-1.39 | 0.32 |
| Negative | ||||
| CA19-9 | ||||
| Positive | <0.01 | 2.26 | 1.06-4.81 | 0.04 |
| Negative | ||||
| p53-Ab | ||||
| Positive | 0.41 | |||
| Negative | ||||
a
Log-rank test analysis;
b
adjusted HR;
c
adjusted 95% CI;
d
Cox proportional hazards regression analysis. CI, confidence interval; HR, hazards ratio. Muc, mucinous adenocarcinoma; Poor, poorly differentiated adenocarcinoma; Tub, tubular adenocarcinoma.