Table III.
Univariate and multivariate analysis of clinicopathological factors to predict overall survival.
| Multivariate analysis | ||||
|---|---|---|---|---|
|
|
||||
| Variable | Univariate P valuea | HRb | 95% CIc | P-valued |
| Sex | ||||
| Male | 0.30 | |||
| Female | ||||
| Age, years | ||||
| <65 | 0.24 | |||
| ≥65 | ||||
| Tumor depth | ||||
| pT3pT4 | <0.01 | 3.85 | 1.14-12.99 | 0.03 |
| pT1pT2 | ||||
| Nodal status | ||||
| Positive | <0.01 | 3.70 | 1.87-7.34 | <0.01 |
| Negative | ||||
| JMJD6-Abs | ||||
| ≥5,720 | 0.03 | 2.14 | 1.16-3.94 | 0.01 |
| <5,720 | ||||
| Distant metastasis | ||||
| Positive | <0.01 | 3.05 | 1.43-6.48 | 0.01 |
| Negative | ||||
| Histology | ||||
| Muc, Poor | 0.28 | |||
| Tub | ||||
| CEA | ||||
| Positive | 0.23 | 0.73 | 0.37-1.48 | 0.39 |
| Negative | ||||
| CA19-9 | ||||
| Positive | <0.01 | 2.13 | 0.98-4.63 | 0.06 |
| Negative | ||||
| p53-Ab | ||||
| Positive | 0.41 | |||
| Negative | ||||
a
Log-rank test analysis;
b
adjusted HR;
c
adjusted 95% CI;
d
Cox proportional hazards regression analysis. CI, confidence interval; HR, hazards ratio. Muc, mucinous adenocarcinoma; Poor, poorly differentiated adenocarcinoma; Tub, tubular adenocarcinoma.