Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
UCH-L1 expression boosts signaling through the Akt. UCH-L1 overexpression may regulate Akt signaling by inhibiting PHLLP1 or PI3K, resulting in increased MAPK signaling, which participates in progression of lymphoma and prostate and gastric cancer. SMAD4, recombinant mothers against decapentaplegic homolog 4; PHLPP1, PH domain and leucine-rich repeat protein phosphatase 1; UCH-L1, ubiquitin C-terminal hydrolase-L1.
