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Immune cells of multiple origins influence the course of NAFLD and HCC. Liver resident and infiltrating immune cells from the circulation are directly implicated in NAFLD and HCC initiation and progression. Abbreviations, ECM, extracellular matrix; HSC, hepatic stellate cell; MoMF, monocyte-derived macrophage; NAFLD, non-alcoholic fatty liver disease; PBMCs, peripheral blood mononuclear cells. Created with BioRender.com.
