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. 2023 Feb 23;13:3138. doi: 10.1038/s41598-023-29868-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of the hippocampal CB1R-immunopositive area. In the CA1 region (a) the CB1R-immunopositive area was decreased in idiopathic epilepsy in comparison to structural epilepsy and controls. In DG (b), CA3 (c) and hilus (d) the area expressing CB1R in idiopathic epilepsy was significantly smaller in comparison to structural epilepsy, but did not differ significantly to controls; error bars indicate SEM and asterisks in the figures indicate significant differences, *p < 0.05, **p < 0.01, ***p < 0.001; CA: Cornu Ammonis; DG: dentate gyrus.