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. 2023 Feb 10;14:1095098. doi: 10.3389/fimmu.2023.1095098

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Copyright © 2023 Zhang, Zhang, Zhang, Song, Bian, Yi and Ma

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of DEGs between UC and control samples. (A) The expression of 65 DEGs was visualized by heatmap. Red for upper regulation, blue for lower regulation (B) Volcano map of DEGs in UC compared to healthy controls. The significantly upregulated DEGs (log2FC>2, adj.P<0.05) were labeled in red, and the significantly downregulated DEGs (log2FC<2, adj.P<0.05) were labeled in blue. (C, D) GO and KEGG enrichment analyses of DEGs. The outermost circle was the GO number, the second circle represented the number of genes on the GO, and the third circle represents the number of genes enriched on the GO. The color represented the p-value of significant enrichment, the redder the color, the more significant the enrichment. (E, F) Results of GSEA pathway analysis in UC and healthy control samples.