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. 2023 Jan 13;60:102609. doi: 10.1016/j.redox.2023.102609

Fig. 6.

Fig. 6

NOX4 deficiency did not affect cellular metabolism. A. Representation of the course of Seahorse XF Cell Mito Stress assay in WT and Nox4 KO primary skin fibroblasts in control conditions and after stimulation with TGF-β2 for 24h; B. Bar graphs representing the average of 3 time points for each measured phase during Seahorse XF Cell Mito Stress assay in WT and Nox4 KO primary skin fibroblasts in control conditions or after stimulation with TGF-β2 for 24h; C. Representation of the course of Seahorse XF Glycolysis Stress assay in WT and Nox4 KO primary skin fibroblasts in control conditions or after stimulation with TGF-β2 for 24h; D. Bar graphs representing the average of 3 time points for each measured phase during Seahorse XF Glycolysis Stress assay in WT and Nox4 KO primary skin fibroblasts in control conditions or after stimulation with TGF-β2 for 24h; WT Control (light green lines and bars) n = 8; WT TGF-β2 (dark green lines and bars) n = 8; Nox4 KO Control (red line and bars) n = 8; Nox4 KO TGF-β2 (dark red lines and bars) n = 8; OCR – oxygen consumption rate, ECAR – extracellular acidification rate; Data shown as mean ± SEM; ns – not significant, *– p < 0.05; 2way ANOVA. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)