Table 5.

Technical information of the technologies used in the studies.

Author	Technology	Class category	Commercial availability	Patent for the technology	Accuracy	Sensitivity	Specificity
L.Cannavò et al. [32]	MRI + CT	2	Yes	N/A	76% to 83%- Radiologist 68% to 72%- (Orthopaedist)	–	–
Anderson et al. [16]	Frozen section	N/A	Yes	Yes	–	–	–
Bajpai et al. [21]	DCE-MRI	2	Yes	N/A	–	–	–
Aszodi et al. [33]	Frozen section	N/A	Yes	Yes	–	–	–
Fayad et al. [22]	MRSI	–	Yes	Yes	–	–	–
Bosma et al. [30]	CT fluoroscopy / intraop. CT	2	Yes	N/A	–	–	–
Boufettal et al. [35]	Isotopic tracking probe using HMDP-99mTc probe	2	Yes	Yes	–	–	–
Cates et al. [24]	Musculoskeletal Tumor Society (MSTS) + American Joint Committee on Cancer (AJCC) R system + margin distance method	–	–	–	–	–	–
Seong Cho et al. [23]	MR images to navigation-assisted bone tumour surgery	2	Yes	Yes	–	–	–
Evrard et al.[31]	MRI + CT + Patient-specific instruments (PSIs)	2	Yes	Yes	–	–	–
Fujiwara et al. [28]	Navigation assisted surgery	–	Yes	Yes	–	–	–
Hodel et al. [29]	CT	N/A	Yes	N/A	–	–	–
Kseniya S. Shin et al [34]	Stimulated Raman scattering (SRS) imaging technique and a new pseudo-H&E recolouring methodology	–	Yes	Yes	69%	58.80%	83.30%
Malek et al. [25]	DW imaging and proton MR spectroscopy	–	510 (K) clearance by FDA	Not found	87% (92% FS)	–	–
Meyer et al. [14]	Frozen section / MRI	N/A	Yes	Yes	–	–	–
Sakamoto et al. [26]	Intra operative specimen MRI	N/A	Yes	Yes	–	–	–
Wong et al. [27]	MRI + CT + 3D software aided visualization for navigation	N/A	Yes	Yes (software)	–	–	–