FIGURE 2.

Pathomics analysis of the PSP tumor. (A) Low-power (4×) photomicrograph showing areas containing tumor (outlined red) and hemosiderin-laden macrophages (outlined blue) as annotated by the pathologist. (B) Tumor with red color density maps showing the number of cells per mm² as identified by the classifier, and shown as percentages (0–100), where the 100% scale value corresponds to 1660 cells per mm², along with intense red coloring. (C) Tumor tissue with blue color density maps showing hemosiderin-laden macrophages where the most intense blue color and scale value of 100% corresponds to 349 cells per mm² (as identified by the classifier). (D) Overlaid density maps for both cell types (same classifier results and color intensity scales as in (B,C).