Table 7.

HR^a estimates related to multistate models for each possible transition, stratified by gender and age group.

CCIb		Male (age 45-59 years), HR (95% CI)c	Male (age 60-74 years), HR (95% CI)c	Female (age 45-59 years), HR (95% CI)c	Female (age 60-74 years), HR (95% CI)c
Positive --> hospitalization
	0	Reference	Reference	Reference	Reference
	1	1.34 (1.15-1.56)	1.19 (1.06-1.33)	1.43 (1.17-1.75)	1.19 (1.01-1.39)
	2-3	1.48 (1.18-1.86)	1.09 (0.96-1.23)	2.49 (1.90-3.26)	1.61 (1.34-1.93)
	4+	2.71 (1.85-3.97)	1.25 (1.04-1.49)	2.42 (1.09.5.33)	2.39 (1.81-3.16)
Positive --> death within 30 days from first infection
	0	Reference	Reference	Reference	Reference
	1	3.87 (0.01-infinity)	0.73 (0.29-1.87)	N/Ad	2.67 (1.05-6.80)
	2-3	1.20 (0.01-infinity)	2.10 (1.03-4.28)	22.57 (2.32-219.69)	4.13 (1.53-11.12)
	4+	220750.22 (0.01-infinity)	3.33 (1.37-8.11)	N/A	7.69 (2.00-29.52)
Hospitalization --> death within 30 days from first infection
	0	Reference	Reference	Reference	Reference
	1	1.42 (0.30-6.61)	1.22 (0.94-1.59)	8.29 (2.81-24.38)	1.40 (0.89-2.21)
	2-3	5.10 (1.34-19.44)	1.92 (1.49-2.49)	0.03 (0.01-37674.39)	1.61 (0.99-2.61)
	4+	728.13 (355.06-1493.24)	2.38 (1.71-3.31)	0.41 (0.01-93403.78)	3.46 (1.98-6.04)

^aHR: hazard ratio.

^bCCI: Charlson Comorbidity Index.

^cEstimated adjusted for age and the month of the first swab.

^dN/A: not applicable.