Skip to main content
. 2023 Feb 23;80(4):342–351. doi: 10.1001/jamaneurol.2023.0033

Table 1. Baseline Participant Characteristics.

Characteristic Participantsa
HIIT (n = 27) MAT (n = 28)
Age, mean (SD), y 63.8 (9.9) 61.5 (9.9)
Sex
Female 11 (40.7) 8 (28.6)
Male 16 (59.3) 20 (71.4)
Race
American Indian 0 1 (3.6)
Asian 0 3 (10.7)
Black/African American 4 (14.8) 7 (25.0)
White 23 (85.2) 17 (60.7)
Hispanic/Latinx ethnicity 1 (3.7) 0
Side of paresis
Left 14 (51.9) 14 (50.0)
Right 13 (48.1) 14 (50.0)
Stroke type
Ischemic 15 (55.6) 19 (67.9)
Hemorrhagic 12 (44.4) 9 (32.1)
Stroke chronicity, mean (SD), y 2.7 (1.4) 2.2 (1.2)
Aphasia present 7 (25.9) 7 (25.0)
Comorbid medical conditions
Any 26 (96.3) 27 (96.4)
History of myocardial infarction 1 (3.7) 2 (7.1)
Atrial fibrillation 2 (7.4) 5 (17.9)
History of lightheadedness and/or syncope 4 (14.8) 5 (17.9)
COPD 3 (11.1) 1 (3.6)
Diabetes
Any 8 (29.6) 9 (32.1)
Insulin dependent 2 (25.0) 2 (22.2)
Arthritis 8 (29.6) 10 (35.7)
History of cancer 4 (14.8) 3 (10.7)
Prescribed medication
Antihypertensive
Any 23 (85.2) 20 (71.4)
β-Blocker 7 (25.9) 11 (39.3)
Statin 22 (81.5) 23 (82.1)
Antispasmodic 11 (40.7) 12 (42.9)
Antidepressant 20 (74.1) 13 (46.4)
Pain reliever 11 (40.7) 11 (39.3)
Reported falling in previous 3 mo 8 (29.6) 7 (25.0)
BMI, mean (SD) 28.9 (5.3) 28.7 (4.6)
Functional ambulation categoryb
Mean (SD) 3.3 (0.6) 3.4 (0.8)
2 2 (7.4) 5 (17.9)
3 14 (51.9) 8 (28.6)
≥4 11 (40.7) 15 (53.6)
Orthotic and/or assistive device use 18 (66.7) 19 (67.9)
Orthotic device use 12 (44.4) 12 (42.9)
Solid ankle foot orthosis 4 (14.8) 2 (7.1)
Articulated or flexible ankle foot orthosis 7 (25.9) 7 (25.0)
Assistive device use
Any 16 (59.3) 18 (64.3)
Single-point cane 8 (29.6) 11 (39.3)
Narrow-based quad cane 5 (18.5) 1 (3.6)
Wide-based quad cane 3 (11.1) 5 (17.9)
Front-wheeled walker 0 1 (3.6)
Fugl-Meyer lower limb motor score, mean (SD)c 23.8 (5.1) 22.8 (5.1)
Self-selected gait speed
Mean (SD), m/s 0.65 (0.29) 0.62 (0.33)
Mean (SD), % normative value 50.5 (23.3) 47.3 (25.1)
<0.4 m/s 7 (25.9) 7 (25.0)
6-min Walk test distance
Mean (SD), m 248 (136) 230 (130)
Mean (SD), % normative value 48.5 (26.3) 44.3 (26.8)
Ventilatory threshold VO2
Mean (SD), mL/kg/min 12.1 (3.9) 11.6 (3.9)
Mean (SD), % normative value 93.1 (24.4) 82.5 (26.2)
Peak VO2
Mean (SD), mL/kg/min 14.3 (4.4) 14.0 (4.8)
Mean (SD), % normative value 60.4 (15.9) 55.1 (19.3)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); COPD, chronic obstructive pulmonary disease; HIIT, high-intensity interval training; MAT, moderate-intensity aerobic training; VO2, oxygen consumption rate.

a

Data are presented as the number (percentage) of participants unless otherwise indicated.

b

Category 2 indicates dependent, level 1 (requires continuous or intermittent light touch to assist balance or coordination from no more than 1 person during ambulation on level surfaces to prevent falling); category 3, dependent, supervision (can physically ambulate on level surfaces without manual contact of another person but requires standby guarding of no more than 1 person because of poor judgment, questionable cardiac status, or the need for verbal cuing to complete the task); and category ≥4, independent, level surfaces (can ambulate independently on level surfaces).

c

Range, 0 to 34; higher scores indicate less motor impairment.