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. 2023 Feb 24;32(3):e4593. doi: 10.1002/pro.4593

TABLE 2.

Biophysical and functional properties of different VHH‐based EGFR × NKp46 NKCE format architectures.

# Yield (mg/L) SEC (%) Mean Tm 1 (°C) HIC retention time (min) EC50killing (pM)
NKp46.2 A eff− 176 92.1 64.5 6.1 0.98
NKp46.26 A eff− 152 86.9 55.4 5.8 4.1
NKp46.2 B eff− 222 91.7 64.1 6.3 0.59
NKp46.26 B eff− 120 94.4 54.9 5.8 0.6
NKp46.2 C eff− 120 94.2 68.5 6.8 1.08
NKp46.26 C eff− 116 96.3 55.6 6.5 0.67
NKp46.2 D eff− 85 93.5 65.5 6.6 4.67
NKp46.26 D eff− 52 98.1 56.0 6.5 4.11