Table 1. Spectroscopic Properties and Photochemical Quantum Yields of Model Caged Conjugates in Water/MeCN (pH 7.4).
| compound | λmax (nm) | λem (nm) | ε × 104 (M–1 cm–1) | Φu (%)a | Φdeg (%)b | ε × Φu (M–1 cm–1)c |
|---|---|---|---|---|---|---|
| 1-A | 538 | 564 | 2.27 | 4.7 | 6.2 | 1 070 |
| 2-A | 570 | 592 | 7.00 | 1.5 | 1.9 | 1020 |
| 3-A | 641 | 674 | 8.60 | 1.7 | 2.2 | 1400 |
| 3-B | 637 | 673 | 7.51 | 0.92 | 1.7 | 690 |
| 3-C | 643 | 676 | 7.33 | 18 | 25 | 13,200 |
a
Uncaging quantum yield, calculated from payload release.
b
Degradation quantum yield, calculated from the disappearance of the conjugates; average of three trials, for the standard deviations, see Table S1 in the SI.
c
Uncaging quantum efficiency at λmax.