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. 2022 Oct 3;1(1):e000309. doi: 10.1136/bmjmed-2022-000309

Table 4.

Example of trial* reporting different outcome data between preprint51 and publication,2 by outcome and treatment group

Outcome Preprint51 Publication2
Mortality Corticosteroids: 454/2104 (21.6)
Standard care: 1065/4321 (24.6)
Corticosteroids: 482/2104 (22.9)
Standard care: 1110/4321 (25.7)
Mechanical ventilation Corticosteroids: 92/1780 (5.2)
Standard care: 258/3638 (7.1)
Corticosteroids: 110/1780 (6.2)
Standard care: 298/3638 (8.2)

Data are events/total number (%) of participants in each treatment group.

*The RECOVERY publication on dexamethasone treatment for covid-19 reported different results for mortality and mechanical ventilation—likely not because of an error in the preprint but because of events accumulating in the trial from when the preprint was posted to when it was published.2 51