TABLE 4.
Multivariable logistic regression analysis of six tag SNPs in males and females.
| SNP | Male | Female | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Genetic model | Genotype | P a | OR (95%CI) a | Genetic model | Genotype | P a | OR (95%CI) a | ||
| rs2280801 | Overdominant | CC + TT | 1.00 | Overdominant | CC + TT | 1.00 | |||
| CT | .110 | 1.581(.901–2.775) | CT | .008 | .515(.315–.844) | ||||
| rs10885 | Dominant | CC | 1.00 | Recessive | CC + CT | 1.00 | |||
| CT + TT | .083 | .531(.259–1.086) | TT | .468 | 1.825(.359–9.277) | ||||
| rs1046089 | Dominant | GG | 1.00 | Recessive | GG + GA | 1.00 | |||
| GA + AA | .018 | .505(.286–.890) | AA | 1.25E-03 | .287(.135–.613) | ||||
| rs2736158 | Dominant | GG | 1.00 | Dominant | GG | 1.00 | |||
| GC + CC | .557 | 1.214(.636–2.318) | GC + CC | .491 | 1.196(.719–1.991) | ||||
| rs1046080 | Dominant | AA | 1.00 | Dominant | AA | 1.00 | |||
| AC + CC | .643 | 1.249(.488–3.196) | AC + CC | .264 | .630(.281–1.416) | ||||
| rs9366785 | Overdominant | GG + AA | 1.00 | Dominant | GG | 1.00 | |||
| GA | 7.00E-04 | 3.280(1.650–6.518) | GA + AA | .208 | 1.408(.827–2.399) | ||||
a
Adjusted for age. SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval.