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. 2023 Feb 24;23:90. doi: 10.1186/s12887-023-03896-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Immune cell infiltration and correlation with genes. A Comparison of 22 immune cell subtypes between KDs and HCs. p-values are obtained by the Wilcoxon test. Pink and turquoise color represent KDs and HCs, respectively (_: non-significant, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001) (The fraction of eosinophils is zero.). The immune cells displayed with red color are upregulated prominently in KD. Correlation between ADM and neutrophils (B); ALPL and neutrophils (C); HK3 and neutrophils (D); MMP9 and neutrophils (E); S100A12 and neutrophils (F). “r” means the correlation coefficient between nodes and immune cells