Table 4. Prevalence of comorbidity in hospitalized COVID-19 patients with COPD.
|
CU-AMC HDC
% (95%CI) |
CUIMC
% (95%CI) |
HealthVerity
% (95%CI) |
IQVIA-OpenClaims
% (95%CI) |
OptumEhr
% (95%CI) |
VA-OMOP
% (95%CI) |
HIRA
% (95%CI) |
SIDIAP
% (95%CI) |
|
| Anxiety | 17.1 (13.3-21.8) | 10.1 (7.6-13.2) | 21.4 (19.5-23.4) | 15.3 (14.9-15.7) | 17.0 (15.9-18.1) | 32.3 (31.0-33.7) | 20.0 (14.3-27.3) | 23.3 (22.1-24.5) |
| Atrial fibrillation | 19.1 (15.0-23.9) | 17.0 (13.8-20.8) | 23.7 (21.7-25.8) | 20.5 (20.0-21.0) | 20.0 (18.9-21.2) | 22.3 (21.1-23.5) | <3.4 | 16.7 (15.7-17.8) |
| Autoimmune condition | 16.7 (12.9-21.3) | 36.7 (32.4-41.3) | 17.3 (15.6-19.2) | 40.0 (39.5-40.6) | 19.1 (18.0-20.3) | 36.9 (35.5-38.3) | 20.7 (14.9-28.0) | 12.7 (11.8-13.7) |
| Bronchiectasis | <3.3 | 3.4 (2.1-5.5) | 1.6 (1.1-2.3) | 1.7 (1.6-1.8) | 1.5 (1.2-1.9) | 0.8 (0.6-1.1) | <3.4 | 5.0 (4.4-5.7) |
| Cancer * | 26.4 (21.7-31.7) | 35.3 (31.0-39.8) | 15.1 (13.5-16.9) | 32.5 (32.0-33.0) | 28.8 (27.5-30.1) | 40.3 (38.9-41.7) | 20.0 (14.3-27.3) | 22.4 (21.2-23.6) |
| Cardiac arrhythmia | 31.8 (26.8-37.3) | 25.5 (21.7-29.7) | 31.6 (29.4-33.9) | 31.1 (30.6-31.6) | 33.3 (31.9-34.7) | 31.9 (30.6-33.3) | 9.7 (5.9-15.6) | 29.6 (28.3-30.9) |
| Cerebrovascular disease | 7.4 (4.9-10.9) | 11.4 (8.8-14.7) | 11.0 (9.6-12.6) | 12.4 (12.0-12.8) | 9.2 (8.4-10.1) | 9.8 (9.0-10.7) | 13.1 (8.6-19.6) | 3.8 (3.3-4.4) |
| Chronic Liver Disease | 4.3 (2.5-7.2) | 4.7 (3.1-7.1) | 4.1 (3.2-5.2) | 3.1 (2.9-3.3) | 3.4 (2.9-4.0) | 9.1 (8.3-10.0) | 10.3 (6.3-16.3) | 1.9 (1.6-2.3) |
| CKD * | 34.4 (29.2-40.0) | 47.7 (43.1-52.3) | 36.7 (34.4-39.1) | 47.7 (47.1-48.3) | 40.8 (39.4-42.2) | 47.3 (45.9-48.7) | 17.2 (11.9-24.2) | 25.2 (24.0-26.4) |
| Depression | 18.4 (14.4-23.2) | 17.0 (13.8-20.8) | 14.6 (13.0-16.4) | 12.7 (12.3-13.1) | 14.1 (13.1-15.2) | 19.7 (18.6-20.9) | 6.9 (3.8-12.2) | 14.8 (13.8-15.8) |
| Heart disease * | 66.9 (61.4-72.0) | 83.4 (79.7-86.6) | 66.3 (64.0-68.5) | 86.1 (85.7-86.5) | 70.7 (69.3-72.0) | 83.0 (81.9-84.1) | 38.6 (31.1-46.7) | 49.6 (48.2-51.0) |
| Heart failure | 22.7 (18.3-27.8) | 27.1 (23.2-31.4) | 35.8 (33.5-38.1) | 33.2 (32.7-33.7) | 26.4 (25.1-27.7) | 28.4 (27.1-29.7) | 15.2 (10.3-21.9) | 14.0 (13.1-15.0) |
| Hypertension * | 75.9 (70.7-80.4) | 90.8 (87.8-93.1) | 75.3 (73.2-77.3) | 93.0 (92.7-93.3) | 79.9 (78.7-81.0) | 93.0 (92.2-93.7) | 55.9 (47.8-63.7) | 41.1 (39.7-42.5) |
| Interstitial lung disease | <3.3 | 3.1 (1.8-5.1) | 3.5 (2.7-4.5) | 4.6 (4.4-4.8) | 3.2 (2.7-3.8) | 2.1 (1.7-2.6) | <3.4 | 0.8 (0.6-1.1) |
| Myocardial infarction | 17.1 (13.3-21.8) | 11.9 (9.2-15.2) | 8.8 (7.5-10.3) | 9.1 (8.8-9.4) | 14.3 (13.3-15.3) | 9.8 (9.0-10.7) | <3.4 | 3.6 (3.1-4.2) |
| Obesity | 50.5 (44.9-56.1) | 58.2 (53.6-62.7) | 25.7 (23.6-27.9) | 38.8 (38.3-39.3) | 58.3 (56.9-59.7) | 55.0 (53.6-56.4) | - | 57.7 (56.3-59.1) |
| Sleep apnea | 22.1 (17.8-27.1) | 9.2 (6.9-12.2) | 13.5 (11.9-15.2) | 11.6 (11.2-12.0) | 13.9 (12.9-14.9) | 29.7 (28.4-31.0) | - | 8.3 (7.6-9.1) |
| T2DM * | 40.5 (35.1-46.2) | 58.8 (54.2-63.3) | 48.6 (46.2-51.0) | 63.0 (62.5-63.5) | 44.6 (43.1-46.1) | 61.6 (60.2-63.0) | 57.2 (49.1-65.0) | 25.6 (24.4-26.9) |
*Prevalent conditions measured any time in the past, others within the previous year. Grey =US database. Pink=South Korean database. Yellow=European database. CKD=Chronic kidney disease. T2DM=type 2 diabetes mellitus.