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. 2023 Feb 9;15:1116516. doi: 10.3389/fnagi.2023.1116516

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Copyright © 2023 Chen, Zhang, Mao, Chen, Shi, Meng, Wang, Hu and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROI-based QSM analysis. Regional mean QSM values in (A) the fear circuit ROIs and (B) iron deposition-based ROIs. Error bars signify the standard error of the mean. Stars denote significant differences between the groups: *Bonferroni-corrected p < 0.05; **Bonferronicorrected p < 0.01. QSM, quantitative susceptibility mapping; ROI, region of interest; PD-A, Parkinson’s disease with anxiety; PD-NA, Parkinson’s disease without anxiety; HC, healthy control; mPFC, medial prefrontal cortex; ACC, anterior cingulate cortex; SN, substantia nigra; RN, red nucleus; GP, globus pallidus.