Table 1.

Description of included studies.

AUTHOR (YEAR)	COUNTRY	CONDITION OR RISK FACTOR	OUTCOME EXTRACTED	STUDY SETTING	INTERVENTION	RECOMMENDATIONS ACCEPTED BY PHYSICIAN	METHOD OF COLLABORATION
Albsoul-Younes, 2011	Jordan	Hypertension	Change in BP	Co-location- unclear	Patient education and counselling, assessing medication regimen (noted patient medication history), adherence assessment, physical assessment.	65 (101/161)	Verbal: face to face – unclear
Aguiar, 2018	Brazil	Type 2 Diabetes	Change in BP, LDL, HbA1c	Separate	Patient education and counselling, assessing medication regimen, adherence assessment.	Not documented	Unclear
Amariles, 2012	Spain	CVD	Change in BP, TC	Separate- unclear	Patient education and counselling, assessing medication regimen, physical assessment.	Not documented	Unclear
Anderegg, 2018	United States of America	Type 2 Diabetes and Chronic Kidney Disease	Change in BP	Co-location	Patient education and counselling, assessing medication regimen, individualised care plan.	Not documented	Verbal or by electronic communication
Bogden, 1997	United States of America	Hypercholesterolemia	Change in TC	Co-location	Patient education and counselling, assessing medication regimen, physical assessment (were done but not clear if it was by pharmacist).	90 (167/186)	Verbal: face to face – unclear
Bogden, 1998	United States of America	Hypertension	Change in BP	Co-location	Patient education and counselling, assessing medication regimen, physical assessment (were done but not clear if it was by pharmacist).	93 (150/162)	Verbal: face to face – unclear
Borenstein, 2003	United States of America	Hypertension	Change in BP	Separate	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	Not documented	Verbal: phone
Carter, 1997	United States of America	Hypertension	Change in BP	Separate but in the same building	Patient education and counselling, assessing medication regimen, adherence assessment. (questioned about adherence), physical assessment.	Not documented	Verbal: mostly face to face but some over the phone (immediate) and written feedback too
Carter, 2008	United States of America	Hypertension	Change in BP	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment, (some, not all allowed) independent prescribing, physical assessment.	96 (256/267)	Verbal: face to face
Carter, 2009	United States of America	Hypertension	Change in BP	Co-location	Assessing medication regimen, physical assessment.	96 (742/771)	Verbal: face to face
Carter, 2015	United States of America	Hypertension	Change in BP	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	Not documented	Mostly verbal: face to face, some written: email
Choe, 2005	United States of America	Type 2 diabetes	Change in HbA1C	Co-location	Patient education and counselling, assessing medication regimen, physical assessment (upon need).	Not documented	Verbal: face to face
Ebid, 2020	Egypt	Type 2 Diabetes	Change in LDL, HDL, HbA1c, BMI	Co-location	Patient education and counselling, assessing medication regimen, physical assessment, adherence assessment.	Not documented	Unclear
Fornos, 2006	Spain	Type 2 diabetes	Change in BP, TC, LDL, HDL, TRIG, HbA1C, BMI	Separate	Patient education and counselling, assessing medication regimen, physical assessment, adherence assessment.	Not documented	Unclear
Geurts, 2016	Netherlands	CVD	Change in BP, TC, LDL, HDL, HbA1C, BMI	Separate	Assessing medication regimen, physical assessment.	Not documented	Written: webbased pharmaceutical care plan tool
Hammad, 2011	Jordan	Metabolic syndrome	Change in BP, HDL, TRIG, WEIGHT AND CM	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment (?), physical assessment.	70 (128/182)	Verbal
Hirsch, 2014	United States of America	Hypertension	Change in BP, LDL, HDL	Co-location	Patient education and counselling, assessing medication regimen (noted patient medication history) adherence assessment, physical assessment, independent prescribing.	Not documented	physician was always present in the medical practice during the pharmacist clinic visits and was available for consultation as needed.
Hunt, 2008	United States of America	Hypertension	Change in BP	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment, independent prescribing.	Not documented	Written: emr (note documented and forwarded to PCP for approval and signature, verbal: face to face – not clarified (if needed)
McKenney, 1973	United States of America	Hypertension	Change in BP	Separate	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	100 (37/37)	written and verbal
Odegard, 2005	United States of America	Type 2 diabetes	Change in HbA1C	Co-location	Patient education and counselling (?), assessing medication regimen, adherence assessment, physical assessment (?).	Not documented	EMR
Rothman, 2005	United States of America	Type 2 diabetes (poorly controlled)	Change in BP, TC, HbA1C, WEIGHT	Co-location	Patient education and counselling, assessing medication regimen, physical assessment, independent prescribing (with approval of PCP).	Not documented	Written (results shared and written approval for medication change) & verbal: face to face (could be in the consult with the physician) or phone (could call them for approval)
Scott, 2006	United States of America	Type 2 diabetes	Change in BP, LDL, HDL, HbA1C, WEIGHT AND BMI	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment (?), physical assessment, independent prescribing (?).	Not documented	not specified
Siaw, 2017	Singapore	Type 2 Diabetes	Change in BP, LDL, HbA1c, costs	Co-location	Patient education and counselling, assessing medication regimen, physical assessment, optimising medication dosing and frequency.	Not documented	Written
Simpson, 2011	Canada	Type 2 diabetes patients with hypertension	Change in BP, TC, LDL, HDL, TRIG, HbA1C, BMI	Co-location	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	Not documented	Verbal
Sookaneknun, 2004	Thailand	Hypertension	Change in BP	Separate	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	47 (96/206)	Written: letter and medical record note
Tobari, 2010	Japan	Hypertension	Change in BP, BMI, SMOKING CESSATION	Co-location	Patient education and counselling, assessing medication regimen adherence assessment, physical assessment.	Not documented	EMR and verbal (if necessary): phone or face to face
Zillich, 2005	United States of America	Uncontrolled hypertension	Change in BP	Separate	Patient education and counselling, assessing medication regimen, adherence assessment, physical assessment.	75 (43/57)	Written: EMR and verbal: phone