Table 1.

Functional modules evoked by UVA exposure. Positive z-score indicates the activation pathway; negative z-score indicates the downregulation of the pathway (the analysis was performed by IPA (Qiagen) using the quantitative LFQ dataset).

	Z-Score
Canonical Pathways	UVA_48h	P_UVA_48h	UVA_D7	P_UVA_D7
Oxidative Phosphorylation	5.39	−1.16	4.71	−1.67
Hepatic Fibrosis Signaling Pathway	2.41	−1.60	1.57	−2.31
Wound Healing Signaling Pathway	1.53	−2.53	1.61	−3.16
Estrogen Receptor Signaling	3.14	−2.11	1.89	−2.89
Macropinocytosis Signaling	2.45	−2.45	2.24	−2.45
GP6 Signaling Pathway	2.14	−1.63	0.91	−2.12
Pulmonary Fibrosis Idiopathic Signaling Pathway	1.23	−2.31	1.00	−2.53
G Beta Gamma Signaling	2.11	−2.65	0.91	−2.65
Gαi Signaling	1.90	−2.45	1.51	−2.45
Regulation of eIF4 and p70S6K Signaling	1.67	−2.45	1.73	−2.45
p70S6K Signaling	1.90	−2.45	1.39	−2.24
Thrombin Signaling	1.51	−2.83	0.91	−2.65
NF-κB Activation by Viruses	1.89	−2.24	1.41	−2.24
Regulation of Cellular Mechanics by Calpain Protease	2.12	−1.89	0.91	−2.45
Glioma invasiveness Signaling	1.89	−2.45	0.63	−2.24
HGF Signaling	1.16	−2.45	0.28	−2.45
UVA-induced MAPK signaling	1.13	−2.00	1.13	−2.00
CDK5 Signaling	1.51	−2.24	0.26	−2.24
PEDF Signaling	1.14	−1.63	0.71	−2.24
Fc Epsilon RI signaling	−1.13	−2.-24	0.38	−2.-24
Glycolysis I	−3.46	1.41	−3.61	2.83
PTEN Signaling	−1.73	2.65	−1.16	2.45
Epithelial Adherens Junction Signaling	−2.20	1.27	−2.35	2.00
CLEAR Signaling Pathway	−1.67	1.70	−1.41	2.45
Gluconeogenesis I	−2.11	2.45	−2.11	2.83
Sirtuin Signaling Pathway	−0.85	−2.32	−1.26	−0.83
Apotosis	1.25	−0.94	2.19	−2.82