Figure 2.

Animal weights. Animal weights were taken at each timepoint to compare weights of animals with doxorubicin administration with (doxo + ET) and without (doxo) ET supplementation with untreated (saline control) animals. Mice administered with doxorubicin had a significant decline in mean body weight compared with saline controls. Doxorubicin-treated animals supplemented with ET also had significant declines in body weight; however, their body weights were able to recover, being significantly greater than doxorubicin-treated animals alone by week 8. A 2-way analysis of variance (ANOVA) using multiple column comparison was performed with significances of **** p < 0.0001, *** p < 0.001 vs. saline control, and # p < 0.05 vs. doxorubicin alone.