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. 2023 Jan 17;12(2):190. doi: 10.3390/antibiotics12020190

Table 2.

Inhibition activity of meleagrin and its chemically prepared derivatives. This table was prepared based on information from Zheng et al., (2013) [59].

FabI inhibitors Chemical structure MIC (μg/mL) IC50 (μM)
S. aureus RN4220 E. coli KCTC 1924 [14C] acetate incorporation
Meleagrin graphic file with name antibiotics-12-00190-i004.jpg 64 32 64
Compound 2 graphic file with name antibiotics-12-00190-i005.jpg 64 64 64
Compound 3 graphic file with name antibiotics-12-00190-i006.jpg 64 32 64
Compound 4 graphic file with name antibiotics-12-00190-i007.jpg 64 32 64
Compound 5 graphic file with name antibiotics-12-00190-i008.jpg 16 8 16
Compound 6 graphic file with name antibiotics-12-00190-i009.jpg 16 8 16
Compound 7 graphic file with name antibiotics-12-00190-i010.jpg >128 >128 >128