Table 3.
Redox metabolism and autophagy as cancer targets for nanoparticle-mediated targeting in different cells.
| Nanoparticle | Model | Redox Mechanism | Autophagic Condition |
Reference |
|---|---|---|---|---|
| Silver | Human neuroblastoma cancer cell line (SH-SY5Y) | Cellular redox homeostasis | Autophagy inhibition | [96] |
| Gold | Bulk cancer cells and cancer stem cells in breast carcinoma | Redox homeostasis | Autophagy modulation | [97] |
| Zinc oxide | MG63 human osteosarcoma cells | Suppressed P13K/AKT/mTOR signaling | Autophagy induction | [98] |
| Magnetic iron oxide | RAW264.7 cells | ER stress homeostasis | Autophagy induction | [99] |
| PEGylated gelatin | MCF-7 cells | Targeting sequestosome 1 (SQSTM1) and cathepsin F | Autophagy induction | [100] |