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. 2023 Feb 2;12(2):302. doi: 10.3390/antibiotics12020302

Table 1.

Characteristics of the participants and clinical data in the pre- and post-AST periods.

Characteristic Total
n = 264 (Patients)
Pre-AST
n = 208 (Episodes)
Post-AST
n = 311 (Episodes)
p-Value
Age (years) 72.5 (24.0–94.0) 71.0 (24.0–94.0) 71.0 (30.0–90.0) 0.616
Sex (male) 157 (59.5) 128 (61.5) 167 (53.7) 0.077
BMI (kg/m2) 20.7 (12.9–42.1) 19.8 (12.9–40.0) 20.9 (13.9–42.1) <0.001 *
CKD 89 (33.7) 96 (46.2) 135 (43.4) 0.537
Diabetes mellitus 31 (11.7) 35 (16.8) 23 (7.4) 0.001 *
COPD 7 (2.7) 11 (5.3) 4 (1.3) 0.013 *
Hematologic disease
Acute myeloid leukemia 77 (29.2) 69 (33.2) 101 (32.5) 0.868
Myelodysplastic syndrome 30 (11.4) 23 (11.1) 42 (13.5) 0.409
Acute lymphocytic leukemia 10 (3.8) 3 (1.4) 20 (6.4) 0.008 *
Malignant lymphoma 84 (31.8) 64 (30.8) 91 (29.3) 0.713
Multiple myeloma 21 (8.0) 16 (7.7) 26 (8.4) 0.785
Aplastic anemia 8 (3.0) 13 (6.3) 12 (3.9) 0.212
Others 34 (12.9) 20 (9.6) 19 (6.1) 0.138

Number (%) or median (interquartile range). Abbreviations are as follows: BMI, body mass index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease. CKD was defined by eGFR of <60 mL/min/1.73 m2 as G3–G5 level as per the KDIGO guidelines. * p < 0.05.