Table 3.
Post-Systemic Metronidazole Plus Amoxicillin/Clavulanic Acid | |||
---|---|---|---|
Microbial Species | Baseline | 1 Month Post-Treatment | 1 Year Post-Treatment |
Periodontal Pathogens: | |||
Aggregatibacter actinomycetemcomitans | 7 (2.9) § | 0 § | 1 (0.01) § |
Porphyromonas gingivalis | 1 (14.3) | 0 | 0 |
Prevotella intermedia/nigrescens | 8 (6.2) | 0 | 3 (2.3) |
Parvimonas micra | 7 (9.6) | 4 (3.2) | 1 (21.6) |
Campylobacter rectus | 9 (2.7) | 4 (0.4) | 4 (2.5) |
Superinfecting Species: | |||
enteric rods/pseudomonads | 1 (0.5) § | 2 (18.7) § | 2 (7.2) § |
staphylococci | 0 | 0 | 1 (2.7) |
Enterococcus faecalis | 0 | 0 | 0 |
Candida species | 0 | 2 (0.03) | 3 (0.02) |
Mean % total recovery of test periodontal pathogens and superinfecting species (SD) † | 18.2 (10.6) | 1.3 (2.4) * | 3.5 (3.1) * |
No. (%) of patients with high-risk subgingival microbiota ‡ | 10 (100) | 2 (20.0) * | 4 (40.0) * |
Mean % recovery of viridans streptococci (SD) | 5.7 (3.4) | 18.5 (14.4) * | 19.1 (22.7) * |
See Table 2 footnote for symbol definitions.