Table 5.

Relationship between high-risk subgingival microbiota and clinical periodontal disease resolution.

		Mean No. of Periodontal Sites/Patient with PD ≥ 5 mm and BOP (SD)
High-Risk Subgingival Microbiota ‡ Detected at 1 Month and/or 1 Year Post-Treatment	No. of Patients	1 Year Post-Treatment	5 Years Post-Treatment
Yes	12	3.2 (2.8)	2.9 (2.1)
No	23	0.7 (0.9) *	0.8 (1.1) *

^‡ Defined as cultivable presence of either A. actinomycetemcomitans and/or P. gingivalis, and/or cultivable recovery of P. intermedia/nigrescens at ≥2.5%, P. micra at ≥3.0%, C. rectus at ≥2.0%, and/or either Gram-negative enteric rods/pseudomonads, staphylococci, or Candida species at ≥5.0%, of total subgingival viable counts, PD: probing depth, BOP: bleeding on probing, * Significantly different from positive patients (p < 0.05).