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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Three-dimensional structure of Miner1 (a), encoded by the CISD2 gene (PDB ID 3FNV), and chemical structures of the natural compound hesperidin, and its derivative hesperetin (b), the latter of which has been shown to interfere with gene expression and promote rejuvenation.