α-KG |
α-ketoglutarate |
AHR |
Aryl hydrocarbon receptor |
APCs |
Antigen presenting cells |
ARE |
Antioxidant response elements |
DNMT |
DNA methyltransferase |
EGFR |
Epidermal growth factor receptor |
GABPA |
GA-binding protein A |
GLUT |
Glucose transporter |
GBM |
Glioblastoma |
GSCs |
Glioblastoma stem cells |
GSH |
Glutathione |
H3K4me3 |
Trimethylation of histone H3 Lys4 |
HIFs |
Hypoxia inducible factors |
HO-1 |
Heme oxygenase-1 |
HRE |
Hypoxia response-element |
Hsps |
Heat shock proteins |
IDH |
Isocitrate dehydrogenase |
IDH-mut |
IDH-mutated |
IDH-wt |
IDH-wild type |
IL-10 |
Interleukin-10 |
IL-23 |
Interleukin-23 |
IRF-8 |
Interferon regulatory factor 8 |
JHDM |
Jumonji-domain histone demethylase |
KDM |
Lysine-specific demethylase |
LSD1 |
Demethylation functions of histone demethylase 1 |
miRNA |
MicroRNA |
NO |
Nitric oxide |
NOS |
NO synthase |
NRF2 |
Nuclear factor erythroid-derived 2-like 2 |
PHD |
Prolyl hydroxylases |
PKM |
Pyruvate kinase M1/2 |
PPP |
Pentose phosphate pathway |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen species |
SAM |
S-adenosyl methionine |
SIRT1 |
Sirtuin |
TAMs |
Tumor-associated macrophages |
TCA |
Tricarboxylic acid |
TDO |
Tryptophan 2,3-dioxygenase activation |
TERT |
Telomerase reverse transcriptase |
TET |
Ten-eleven translocation enzymes |
TGF-β |
Transforming growth factor-beta |
TME |
Tumor microenvironment |
Tregs |
Regulatory T cells |
Trx |
Thioredoxin |
2-HG |
2-hydroxyglutarate |