Table 4.
Different polymer-based medical devices approved to use in clinical trials.
| Device | Description | Application | Identifier | Ref. |
|---|---|---|---|---|
| 3D-Printed Scaffold |
Polycaprolactone Tricalcium Phosphate (PCL-TCP) is a bioactive, biocompatible, and bioabsorbable non-toxic polymer compound. | Ridge preservation after tooth extraction. | NCT03735199 | [198] |
| Neuro-spinal Scaffold |
Poly (lactic-co-glycolic acid)-b-poly (L-lysine) scaffold | Thoracic AIS A traumatic spinal cord injury at neurological level of injury of T2-T12. | NCT02138110 | [199,200] |
| Absorb GT1 BVS | Absorb GT1 Bioresorbable Vascular Scaffold (BVS) | Ischemic heart disease, angina pectoris, coronary artery disease, coronary artery occlusion, myocardial ischemia | NCT03409731 | [201] |
| Bio ACL | Collagen based-membrane derived from amniotic tissue | anterior cruciate ligament rupture | NCT03294759 | [202,203] |
| BMAC Nerve Allograft | Decellularized processed peripheral nerve allograft, with autologous bone marrow aspirate concentrate. | Peripheral nerve injury, upper limb | NCT03964129 | [204] |
| Bioactive glass scaffold | Bioactive glass scaffold with multi-scale porosity prepared using the sol-gel technique. | Bone loss, vertical alveolar bone loss, horizontal alveolar bone loss | NCT01878084 | [205] |
| ABSORB scaffold |
Everolimus-eluting bioresorbable vascular scaffold | Cardiac allograft vasculopathy | NCT02377648 | [206,207] |
| SERI® Surgical Scaffold | Bioresorbable scaffold derived from silk, developed to provide support and repair of soft tissues | Breast reconstruction | NCT01256502 | [208] |
| Chitosan scaffold |
Bilaminar chitosan scaffold | Sellar floor repair in endoscopic endonasal transsphenoidal surgery | NCT03280849 | [209] |
| Nanofiber scaffold |
Rotium nanofiber is an FDA approved scaffold. | Rotator cuff tears | NCT04325789 | [210] |
| Bioresorbable vascular scaffold |
The bioresorbable vascular scaffold (BVS) has been approved and is used in daily clinical practice. | Coronary thrombosis, tomography, optical coherence drug-eluting stents |
NCT03180931 | [211,212] |
| Firesorb | Sirolimus Target Eluting Bioresorbable Vascular Scaffold | Coronary artery disease | NCT02890160 | [213] |