Table 1.
Evolution of the consumption of antibacterials for systemic use (ATC group J01) in the community in Navarre per quarters (DID and number of patients).
| 1st Quarter | 2nd Quarter | 3rd Quarter | 4th Quarter | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018 | 2019 | 2020 | 2021 | 2018 | 2019 | 2020 | 2021 | 2018 | 2019 | 2020 | 2021 | 2018 | 2019 | 2020 | 2021 | p * | |
| Defined daily doses per 1000 inhabitants per day (DID) | |||||||||||||||||
| J01A—Tetracyclines | 1.04 | 1.15 | 1.24 | 1.60 | 0.96 | 1.02 | 0.93 | 1.22 | 0.66 | 0.77 | 0.79 | 0.83 | 0.99 | 1.17 | 1.25 | 1.24 | 0.796 |
| J01C—Betalactams. Penicillins | 11.00 | 10.52 | 10.04 | 4.97 | 8.85 | 9.16 | 4.86 | 5.26 | 7.55 | 7.52 | 5.06 | 5.14 | 9.50 | 9.28 | 5.09 | 7.23 | 0.010 |
| J01D—Other betalactam antibacterials | 2.66 | 2.31 | 2.46 | 1.62 | 1.99 | 1.98 | 1.45 | 1.68 | 1.80 | 1.83 | 1.69 | 1.72 | 2.19 | 2.24 | 1.69 | 2.09 | 0.051 |
| J01E—Sulfonamides and trimethoprim | 0.31 | 0.33 | 0.41 | 0.40 | 0.31 | 0.36 | 0.36 | 0.40 | 0.29 | 0.39 | 0.36 | 0.41 | 0.30 | 0.40 | 0.38 | 0.39 | 0.962 |
| J01F—Macrolides. Lincosamides and streptogramins | 2.74 | 2.19 | 2.22 | 0.98 | 1.92 | 1.72 | 0.94 | 1.03 | 1.62 | 1.38 | 0.82 | 0.87 | 2.09 | 1.92 | 0.95 | 1.50 | 0.011 |
| J01M—Quinolones | 2.99 | 2.12 | 1.66 | 0.92 | 1.95 | 1.60 | 0.89 | 0.89 | 1.78 | 1.29 | 0.92 | 0.91 | 1.79 | 1.41 | 1.00 | 1.20 | 0.011 |
| J01X—Other antibacterials | 0.38 | 0.42 | 0.45 | 0.46 | 0.40 | 0.43 | 0.43 | 0.45 | 0.43 | 0.48 | 0.48 | 0.48 | 0.42 | 0.47 | 0.46 | 0.47 | 0.078 |
| TOTAL | 21.13 | 19.05 | 18.48 | 10.95 | 16.37 | 16.27 | 9.85 | 10.93 | 14.13 | 13.65 | 10.11 | 10.35 | 17.29 | 16.90 | 10.83 | 14.12 | 0.007 |
| Number of patients | |||||||||||||||||
| J01A—Tetracyclines | 1325 | 1436 | 1550 | 1878 | 1364 | 1404 | 1277 | 1680 | 975 | 1075 | 1093 | 1151 | 1284 | 1465 | 1573 | 1516 | 0.643 |
| J01C—Betalactams. Penicillins | 45,217 | 43,171 | 42,977 | 19,741 | 37,023 | 38,970 | 19,170 | 21,891 | 30,881 | 30,950 | 20,373 | 21,317 | 41,118 | 41,063 | 20,391 | 31,333 | 0.008 |
| J01D—Other betalactam antibacterials | 11,008 | 9554 | 10,427 | 6839 | 8350 | 8333 | 6112 | 7185 | 7706 | 7738 | 7333 | 7395 | 9424 | 9581 | 7365 | 9025 | 0.056 |
| J01E—Sulfonamides and trimethoprim | 833 | 941 | 1280 | 1167 | 932 | 1087 | 1100 | 1237 | 890 | 1234 | 1109 | 1275 | 910 | 1298 | 1166 | 1243 | 0.817 |
| J01F—Macrolides. Lincosamides and streptogramins | 23,083 | 17,043 | 17,527 | 5602 | 15,184 | 13,231 | 5843 | 6430 | 13,091 | 10,107 | 5042 | 5402 | 17,593 | 15,518 | 5855 | 12,040 | 0.013 |
| J01M—Quinolones | 16,949 | 11,645 | 9241 | 4707 | 11,010 | 8814 | 4737 | 4667 | 10,090 | 7155 | 4865 | 4804 | 10,289 | 7948 | 5258 | 6641 | 0.010 |
| J01X—Other antibacterials | 7940 | 8773 | 9723 | 9888 | 8413 | 9206 | 9196 | 9693 | 9399 | 10,397 | 10,730 | 10,618 | 9256 | 10,298 | 10,287 | 10,131 | 0.019 |
| TOTAL | 92,186 | 80,882 | 79,952 | 43,256 | 71,561 | 71,035 | 40,809 | 46,108 | 63,529 | 60,179 | 43,869 | 45,160 | 77,921 | 75,839 | 44,964 | 62,580 | 0.007 |
* Comparing periods pre-pandemic and pandemic.