Table 2.
1st Quarter | 2nd Quarter | 3rd Quarter | 4th Quarter | p * | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2019 | 2021 | Variation | 2019 | 2021 | Variation | 2019 | 2021 | Variation | 2019 | 2021 | Variation | |||
J01CA04—Amoxicillin | DID | 5.044 | 1.989 | −61% | 4.247 | 2.189 | −48% | 3.220 | 1.947 | −40% | 4.668 | 3.375 | −28% | 0.017 |
Patients | 23,571 | 8636 | −63% | 20,277 | 10,152 | −50% | 14,637 | 8889 | −39% | 22,833 | 16,544 | −28% | 0.013 | |
J01CR02—Amoxicillin + clavulanic acid | DID | 4.997 | 2.737 | −45% | 4.377 | 2.826 | −35% | 3.875 | 2.903 | −25% | 4.072 | 3.525 | −13% | 0.003 |
Patients | 17,761 | 10,264 | −42% | 15,867 | 10,851 | −32% | 14,274 | 11,205 | −22% | 15,520 | 13,678 | −12% | 0.003 | |
J01DC02—Cefuroxime | DID | 1.556 | 1.117 | −28% | 1.324 | 1.160 | −12% | 1.249 | 1.176 | −6% | 1.522 | 1.434 | −6% | 0.048 |
Patients | 6093 | 4389 | −28% | 5249 | 4604 | −12% | 4924 | 4732 | −4% | 6111 | 5871 | −4% | 0.042 | |
J01FA10—Azithromycin | DID | 1.525 | 0.513 | −66% | 1.165 | 0.533 | −54% | 0.894 | 0.474 | −47% | 1.338 | 1.054 | −21% | 0.044 |
Patients | 14,780 | 4158 | −72% | 11,336 | 4856 | −57% | 8388 | 4041 | −52% | 13,409 | 10,446 | −22% | 0.017 | |
J01MA12—Levofloxacin | DID | 1.099 | 0.384 | −65% | 0.765 | 0.371 | −52% | 0.550 | 0.367 | −33% | 0.688 | 0.587 | −15% | 0.022 |
Patients | 5787 | 1864 | −68% | 4068 | 1861 | −54% | 2799 | 1751 | −37% | 3757 | 3130 | −17% | 0.027 |
* Comparing periods pre-pandemic and pandemic. DID: Defined daily doses per 1000 inhabitants per day.