Table 4.
The calculated IC50 values (μM) of aurein 1.2 and its analogs.
IC50 (μM) |
H838 | U251MG | MCF-7 |
---|---|---|---|
Aurein1-2 | 26.9 ± 0.80 | 38.4 ± 0.24 | 25.9 ± 0.79 |
IK-1 | 3.5 ± 0.74 | 3.4 ± 0.71 | 3.0 ± 0.76 |
IK-2 | 3.7 ± 0.77 | 3.6 ± 0.18 | 3.2 ± 0.87 |
IK-3 | 3.0 ± 0.74 | 3.3 ± 0.63 | 3.4 ± 0.71 |
KLA-1 | 29.4 ± 0.22 | 34.1 ± 0.21 | 17.6 ± 0.79 |
KLA-2 | 4.6 ± 0.12 | 5.0 ± 0.12 | 3.6 ± 0.79 |