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. 2023 Feb 19;12(2):412. doi: 10.3390/antibiotics12020412

Table 4.

The calculated IC50 values (μM) of aurein 1.2 and its analogs.

IC50
(μM)
H838 U251MG MCF-7
Aurein1-2 26.9 ± 0.80 38.4 ± 0.24 25.9 ± 0.79
IK-1 3.5 ± 0.74 3.4 ± 0.71 3.0 ± 0.76
IK-2 3.7 ± 0.77 3.6 ± 0.18 3.2 ± 0.87
IK-3 3.0 ± 0.74 3.3 ± 0.63 3.4 ± 0.71
KLA-1 29.4 ± 0.22 34.1 ± 0.21 17.6 ± 0.79
KLA-2 4.6 ± 0.12 5.0 ± 0.12 3.6 ± 0.79