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. 2023 Feb 15;12(2):389. doi: 10.3390/antibiotics12020389

Table 2.

Fractional inhibitory concentration index (FICI) for antibiotics paired with LL-37 against E. coli and P. aeruginosa lab strains.

FICI
Bacterial Strain Ampicillin Tetracycline Ciprofloxacin Gentamicin Aztreonam Polymyxin B
E. coli MG1655 1 1 0.5 1 0.75 0.37
P. aeruginosa PAO1 n.d. 0.56 0.56 1.5 2 0.31

FICI ≤ 0.5 is synergistic, 0.5 < FICI ≤ 1.0 is additive, 1.0 < FICI ≤ 4.0 is indifferent, and FICI > 4.0 is antagonistic. n.d.: not determined.