| A2AR | adenosine A2A receptor |
| ADCC | antibody-dependent cellular cytotoxicity |
| AML | acute myeloid leukemia |
| APC | antigen-presenting cells |
| ART1 | mono-ADP-ribosyl transferase 1 |
| ATC | activated T cells |
| ATP | adenosine triphosphate |
| (CAR)-T | chimeric antigen receptor T cell |
| CD | cluster of differentiation |
| CRC | colorectal cancer |
| CREB | cAMP response element-binding protein |
| CRISPR | clustered regularly interspaced short palindromic repeats |
| CTL | cytotoxic T lymphocytes |
| CTLA-4 | cytotoxic T-lymphocyte-associated protein 4 |
| DC | dendritic cells |
| DSB | double-strand break |
| EMT | epithelial-to-mesenchymal transition |
| FGL1 | fibrinogen-like protein 1 |
| Gal-9 | galectin-9 |
| GITR | glucocorticoid-induced tumor necrosis factor receptor-related protein |
| GPCR | G-protein-coupled receptor |
| HAVCR2 | hepatitis A virus cellular receptor 2 |
| HCC | hepatocellular carcinoma |
| HDAC | histone deacetylase |
| HIF | hypoxia-inducible factor |
| HLA | human leukocyte antigen |
| HMGB1 | High Mobility Group Box 1 |
| HNSCC | head and neck squamous cell carcinoma |
| IAP | integrin-related protein |
| ICB | immune checkpoint blockade |
| ICI | immune checkpoint inhibitor |
| ICOS | inducible T cell COStimulator |
| IFN γ | interferon-γ |
| IG | immunoglobulin |
| IL-10 | interleukin-10 |
| IL-15R | interleukin15 receptor |
| IL-2 | interleukin-2 |
| IL-4 | interleukin-4 |
| ITIM | immune receptor tyrosine-based inhibitory motif |
| ITSM | immune receptor tyrosine-based switch motif |
| LAG-3 | lymphocyte activation gene-3 |
| MAR | mono-ADP-ribosyl |
| mART | mono-ADP-ribosyl transferase |
| MDSC | myeloid-derived suppressor cells |
| MHC | major histocompatibility complex |
| miRNA | micro-RNA |
| mRNA | messenger RNA |
| MMP | matrix metalloproteinases |
| mAb | Monoclonal antibody |
| NECA | 5′-(N-ethylcarboxamido) adenosine |
| NHL | non-Hodgkin’s lymphoma |
| NICD | NAD+-induced cell death |
| NK | natural killer |
| NKAE | activated and expanded NK cells |
| NKG2D/A | natural killer group 2D/A |
| NKG2DL | NKG2D ligand |
| NSCLC | non-small-cell lung cancer |
| ORR | objective response rate |
| MAR | poly-ADP-ribosyl |
| PARP | poly-ADP-ribose polymerase |
| PD-1 | programmed cell death protein 1 |
| PD-L1/2 | programmed cell death ligand 1/2 |
| PI3K | phosphatidylinositol 3-kinase |
| PKD2 | protein kinase D isoform 2 |
| PRR | pattern recognition receptor |
| PSGL-1 | P-selectin glycoprotein ligand 1 |
| Ptdser | phosphatidylserine |
| PTEN | phosphatase and TENsin homolog |
| PTPase | protein tyrosine phosphatases |
| SCLC | small cell lung cancer |
| SIRPα | signal regulatory protein α |
| STING | stimulator of interferon genes |
| TAA | tumor-associated antigen |
| TCR | T cell receptor |
| TIGIT | T cell immunoreceptor with immunoglobulin and ITIM domain |
| TIL | tumor-infiltrating lymphocyte |
| TIM-3 | T cell immunoglobulin and mucin domain 3 |
| TLR7 | toll-like receptor 7 |
| TME | tumor microenvironment |
| TNBC | triple-negative breast cancer |
| TNF α | tumor necrosis factor-α |
| Treg | regulatory T cell |
| TRIM | T cell interacting molecule |
| TSA | tumor-specific antigen |
| VEGF | vascular endothelial growth factor |
| VISTA | V-domain Ig suppressor of T cell activation |
| WNT | wingless-related integration site |