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. 2023 Jan 30;12(2):218. doi: 10.3390/biology12020218
A2AR adenosine A2A receptor
ADCC antibody-dependent cellular cytotoxicity
AML acute myeloid leukemia
APC antigen-presenting cells
ART1 mono-ADP-ribosyl transferase 1
ATC activated T cells
ATP adenosine triphosphate
(CAR)-T chimeric antigen receptor T cell
CD cluster of differentiation
CRC colorectal cancer
CREB cAMP response element-binding protein
CRISPR clustered regularly interspaced short palindromic repeats
CTL cytotoxic T lymphocytes
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
DC dendritic cells
DSB double-strand break
EMT epithelial-to-mesenchymal transition
FGL1 fibrinogen-like protein 1
Gal-9 galectin-9
GITR glucocorticoid-induced tumor necrosis factor receptor-related protein
GPCR G-protein-coupled receptor
HAVCR2 hepatitis A virus cellular receptor 2
HCC hepatocellular carcinoma
HDAC histone deacetylase
HIF hypoxia-inducible factor
HLA human leukocyte antigen
HMGB1 High Mobility Group Box 1
HNSCC head and neck squamous cell carcinoma
IAP integrin-related protein
ICB immune checkpoint blockade
ICI immune checkpoint inhibitor
ICOS inducible T cell COStimulator
IFN γ interferon-γ
IG immunoglobulin
IL-10 interleukin-10
IL-15R interleukin15 receptor
IL-2 interleukin-2
IL-4 interleukin-4
ITIM immune receptor tyrosine-based inhibitory motif
ITSM immune receptor tyrosine-based switch motif
LAG-3 lymphocyte activation gene-3
MAR mono-ADP-ribosyl
mART mono-ADP-ribosyl transferase
MDSC myeloid-derived suppressor cells
MHC major histocompatibility complex
miRNA micro-RNA
mRNA messenger RNA
MMP matrix metalloproteinases
mAb Monoclonal antibody
NECA 5′-(N-ethylcarboxamido) adenosine
NHL non-Hodgkin’s lymphoma
NICD NAD+-induced cell death
NK natural killer
NKAE activated and expanded NK cells
NKG2D/A natural killer group 2D/A
NKG2DL NKG2D ligand
NSCLC non-small-cell lung cancer
ORR objective response rate
MAR poly-ADP-ribosyl
PARP poly-ADP-ribose polymerase
PD-1 programmed cell death protein 1
PD-L1/2 programmed cell death ligand 1/2
PI3K phosphatidylinositol 3-kinase
PKD2 protein kinase D isoform 2
PRR pattern recognition receptor
PSGL-1 P-selectin glycoprotein ligand 1
Ptdser phosphatidylserine
PTEN phosphatase and TENsin homolog
PTPase protein tyrosine phosphatases
SCLC small cell lung cancer
SIRPα signal regulatory protein α
STING stimulator of interferon genes
TAA tumor-associated antigen
TCR T cell receptor
TIGIT T cell immunoreceptor with immunoglobulin and ITIM domain
TIL tumor-infiltrating lymphocyte
TIM-3 T cell immunoglobulin and mucin domain 3
TLR7 toll-like receptor 7
TME tumor microenvironment
TNBC triple-negative breast cancer
TNF α tumor necrosis factor-α
Treg regulatory T cell
TRIM T cell interacting molecule
TSA tumor-specific antigen
VEGF vascular endothelial growth factor
VISTA V-domain Ig suppressor of T cell activation
WNT wingless-related integration site