. 2023 Feb 15;12(2):391. doi: 10.3390/antibiotics12020391

Table 5.

Synergism of Gram-negative strains for Pln149-PEP20 and vancomycin.

Bacterial Strains	Main Phenotype	Pln149-PEP20 MIC (mg/L)	Vancomycin MIC (mg/L)	Combination (mg/L)		FIC Index
Bacterial Strains	Main Phenotype	Pln149-PEP20 MIC (mg/L)	Vancomycin MIC (mg/L)	MIC_Pln149-PEP20	MIC_Vancomycin	FIC Index
K. pneumoniae ATCC 700603		64	>64	8	2	0.133
K. pneumoniae AMKP7 [18]	KPC+, CL S	512	128	128	16	0.375
K. pneumoniae AMKP4 [18]	KPC+, CL R	512	>64	256	64	0.75
K. pneumoniae AMKP10 [18]	KPC+, CL R	512	>64	512	>64	2
A. baumannii ATCC 19606		32	>64	4	2	0.133
A. baumannii ACI40 [20]	CL S	64	>64	8	2	0.133
A. baumannii ACI50 [20]	CL R	64	>64	2	16	0.093
E. coli ATCC 25922		32	>64	4	2	0.133
P. aeruginosa ATCC 27853	Inducible AmpC	32	>64	32	>64	2

KPC+—Klebsiella pneumoniae Carbapenemase (KPC) Producing Bacteria; CL R—Resistant to colistin; CL S—Sensible to colistin.