Table 4.
List of analytes and mass spectrometry parameters for detection of antibacterial compounds.
| Class | Analyte | Precursor (m/z) | Products 1/2 (m/z) | DP (V) | CE 1/2 (V) |
|---|---|---|---|---|---|
| β-lactams | Amoxycillin * | 366 | 349/208 | 45 | 14/18 |
| Ampicillin * | 350 | 106/160 | 58 | 27/19 | |
| Penicillin G * | 335 | 160/176 | 60 | 17/19 | |
| Penicillin V | 351 | 160/114 | 54 | 17/48 | |
| Oxacillin * | 402 | 160/243 | 50 | 18/18 | |
| Cloxacillin | 436 | 160/277 | 50 | 20/20 | |
| Nafcillin * | 415 | 199/171 | 50 | 20/50 | |
| Dicloxacillin * | 470 | 160/311 | 50 | 20/20 | |
| Cephapirin * | 424 | 154/124 | 50 | 35/70 | |
| Cefoperazone * | 646 | 530/143 | 60 | 17/50 | |
| Cephalexin * | 348 | 158/106 | 50 | 10/23 | |
| Cefquinome * | 529 | 134/125 | 50 | 25/75 | |
| Cefazolin * | 455 | 323/156 | 50 | 15/23 | |
| Cefalonium * | 459 | 337/152 | 46 | 16/28 | |
| Ceftiofur * | 524 | 241/125 | 50 | 25/70 | |
| Sulphonamides | Sulfaguanidine | 215 | 156/108 | 20 | 20/30 |
| Sulfadiazine | 251 | 156/108 | 53 | 22/30 | |
| Sulfathiazole * | 256 | 156/108 | 53 | 20/34 | |
| Sulfamerazine * | 265 | 156/108 | 45 | 25/37 | |
| Sulfamethazine * | 279 | 156/108 | 50 | 25/36 | |
| Sulfamethoxazole * | 254 | 156/108 | 50 | 23/35 | |
| Sulfamethoxypyridazine | 281 | 156/108 | 60 | 25/35 | |
| Sulfamonomethoxine * | 281 | 156/108 | 50 | 23/37 | |
| Sulfadoxine | 311 | 156/108 | 60 | 25/40 | |
| Sulfadimethoxine * | 311 | 156/108 | 50 | 23/37 | |
| Sulfaquinoxaline | 301 | 156/108 | 50 | 23/40 | |
| Diaminopyrimidines | Trimethoprim * | 292 | 231/262 | 52 | 33/36 |
| Macrolides | Tylosin * | 916 | 174/772 | 110 | 52/42 |
| Erythromycin * | 734 | 158/576 | 75 | 42/27 | |
| Spiramycin * | 843 | 174/540 | 120 | 52/44 | |
| Tilmicosin * | 869 | 174/696 | 135 | 61/56 | |
| Josamycin * | 828 | 174/229 | 80 | 46/44 | |
| Tulathromycin | 806 | 577/158 | 95 | 37/59 | |
| (Fluoro)quinolones | Danofloxacin * | 358 | 340/255 | 60 | 33/50 |
| Difloxacin * | 400 | 382/356 | 50 | 30/28 | |
| Enrofloxacin * | 360 | 342/286 | 72 | 30/50 | |
| Ciprofloxacin * | 332 | 314/231 | 61 | 30/47 | |
| Flumequine * | 262 | 244/202 | 44 | 25/45 | |
| Sarafloxacin * | 386 | 368/348 | 50 | 31/46 | |
| Marbofloxacin * | 363 | 345/320 | 70 | 30/22 | |
| Norfloxacin * | 320 | 302/231 | 60 | 33/50 | |
| Oxolinic acid * | 262 | 244/216 | 53 | 25/40 | |
| Nalidixic acid * | 233 | 215/187 | 42 | 30/35 | |
| Pleuromutilines | Tiamulin * | 494 | 192/118 | 128 | 30/56 |
| Valnemulin | 565 | 263/164 | 45 | 20/40 | |
| Tetracyclines | Chlortetracycline * | 479 | 444/462 | 56 | 31/25 |
| Tetracycline * | 445 | 410/427 | 36 | 27/19 | |
| Doxycycline * | 445 | 428/154 | 55 | 25/42 | |
| Oxytetracycline * | 461 | 426/443 | 41 | 27/19 | |
| Aminoglycosides | Streptomycin * | 582 | 263/246 | 166 | 45/52 |
| Dihydrostreptomycin * | 584 | 263/246 | 150 | 42/53 | |
| Gentamycin | 478 | 322/157 | 44 | 22/31 | |
| Paromomycin | 616 | 163/293 | 112 | 49/33 | |
| Spectinomycin * | 351 | 333/207 | 67 | 27/32 | |
| Kanamycin | 485 | 163/205 | 70 | 35/36 | |
| Neomycin * | 615 | 161/163 | 109 | 46/33 | |
| Lincosamides | Lincomycin * | 407 | 126/359 | 74 | 36/28 |
* analytes tested in water.