Table 2.
Association of rs114066381-A with body mass index and fat mass index in unrelated females of the Pelotas cohort and replications.
Phenotype | Cohort | N | Age (years old) | Frequency | Regression coefficient | SE | p value | Power |
---|---|---|---|---|---|---|---|---|
Fat mass index | Pelotas | 1417 | 30 | 0.008 | 2.21 | 0.84 | 9.00e–03 | – |
Body mass index | Pelotas | 1795 | 23 | 0.008 | 3.99 | 0.84 | 2.76e–06 | – |
Bambui | 516 | 60–93 | 0.010 | 2.93 | 2.65 | 0.26 | 39% | |
Bambui (all femalesa) | 821 | 60–93 | 0.009 | 2.64 | 2.33 | 0.25 | 53% | |
Sao Paulo | 651 | 59–99 | 0.019 | 3.34 | 1.12 | 3.26e–03 | 89% | |
Bambui + Sao Paulo | 1173 | 59–99 | 0.015 | 3.55 | 0.94 | 1.91e–04 | 99% | |
Salvador | 664 | 4–11 | 0.021 | −0.24 | 0.38 | 0.53 | 9% | |
Puerto Rico | 1082 | 21–89 | 0.005 | 1.30 | 1.92 | 0.50 | 13% | |
African populationsb (all femalesa) | 1103 | 17–97 | 0.013 | −0.57 | 0.80 | 0.47 | 9% | |
Soweto | 859 | 39–60 | 0.020 | 2.39 | 7.63 | 0.75 | 69% |
Using genetic relationship matrix.
Nigeria, Cameroon, Sudan, Ethiopia, Kenya, Tanzania, and Botswana populations.