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. 2023 Feb 8;12(2):267. doi: 10.3390/biology12020267

Table 2.

Molecular classification of medulloblastoma [2,3,24].

Medulloblastoma, Molecularly Defined Pathway
Group 1 WNT-activated
Group 2 SHH-activated and TP53-wildtype
SHH-activated and TP53-mutant
Group 3 (non-WNT/non-SHH)
Group 4 (non-WNT/non-SHH)

SHH—sonic hedgehog; WHO—world health organization; WNT—wingless/Integration-1.