| [11C]PiB | (11)C-labeled Pittsburgh Compound-B |
| [11C]UCBJ | (4R)-1-[(3-(11C)Methylpyridin-4-yl)methyl]-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one |
| [18F] | fluorine radioisotope |
| [18F]FDG | [18F]Fluorodeoxyglucose |
| [18F]MNI-1126 | 18F analog of [11C]UCB-J PET radioligand |
| [18F]SDM-16 | (4R)-4-(3-fluoro-5-(fluoro-18F)phenyl)-1-((2-methyl-1H-imidazol-1-yl)methyl)pyrrolidin-2-one |
| [18F]SDM-16 | (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one (UIPAC name) |
| [18F]SDM-8 | (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one |
| [18F]SynVesT-1 | (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one |
| [18F]UCB-H | (4R)-1-((3-Fluoranyl-4-pyridyl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one |
| 99-CTF | 99-amino acid membrane bound C-terminal fragment |
| 99-CTF | 99-amino acid membrane-bound C-terminal fragment |
| Aβ | amyloid β |
| AβF | amyloid β fibril |
| AβPF | amyloid β protofibril |
| AD | Alzheimer’s disease |
| ADHD | attention deficit hyperactivity disorder |
| aMCI | amnestic mild cognitive impairment |
| AMPA | α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid |
| AMPAR | α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor |
| APOE3 | apolipoprotein E3 |
| APOE4 | apolipoprotein E4 |
| APP | amyloid-β precursor protein |
| APP | amyloid precursor protein |
| APP669–711 | amyloid-β precursor protein isoforms |
| ATN | (amyloidβ (A), phosphorylated tau (T) and neurodegeneration (N) markers) |
| ATP | adenosine triphosphate |
| AβO(s) | amyloid β oligomer(s) |
| BDNF | brain-derived neurotrophic factor |
| BOLD | blood oxygenation level-dependent |
| bvFTD | behavioural variant of frontotemporal dementia |
| CA1 | hippocampal subfield/region CA1 |
| CaMKII | Ca2+/calmodulin-dependent protein kinase II |
| cdk5 | cyclin-dependent kinase 5 |
| CJD | Creutzfeldt–Jakob disease |
| CREB | cAMP response element-binding protein |
| CSF | cerebrospinal fluid |
| DAB1 | DAB adaptor protein 1 |
| DAB1-P | phosphorylated DAB adaptor protein 1 |
| DMN | default mode network |
| DNA | deoxyribonucleic acid |
| DTI | diffusion tensor imaging |
| EEG | electroencephalogram |
| EM | electron microscopy |
| EMG | electromyography |
| EphB2 | ephrin type-B receptor 2 |
| FAD | familial Alzheimer’s disease |
| FDG-PET | fluorine-18 fluorodeoxyglucose PET imaging |
| fMRI | functional magnetic resonance imaging |
| FYN | proto-oncogene tyrosine-protein kinase Fyn |
| GABA | gamma-aminobutyric acid |
| GABAB | gamma-aminobutyric acid B receptor |
| GAP-43 | growth-associated protein 43 |
| GluA2 | ligand-gated ion channel glutamate receptor |
| GluCEST | glutamate chemical exchange saturation transfer |
| GluN1 | NMDA receptor subunit GluN1 |
| GluN2B | NMDA receptor subunit GluN2B |
| GSK3β | glycogen synthase kinase-3β |
| HT | histochemical techniques |
| IDE | insulin-degrading enzyme |
| IFITM | interferon-induced transmembrane protein |
| IHC | immunohistochemistry |
| IHT | immunohistochemical techniques |
| LilrB2 | leukocyte immunoglobulin-like receptor subfamily B member 2 |
| LOAD | late-onset form |
| LTD | long-term depression |
| LTP | long-term potentiation |
| M1 microglia | microglia releasing inflammatory mediators, promotes inflammation and neurotoxicity |
| M2 microglia | microglia releasing anti-inflammatory mediators, has an anti-inflammatory and neuroprotective effect. |
| MCI | mild cognitive impairment |
| MEG | magnetoencephalography |
| mGluR5 | metabotropic glutamate receptor 5 |
| miRs | microRNAs |
| MMT | memory manifold theory |
| MMT | memory manifold theory |
| MRS | MR spectroscopy |
| MT | mitochondria(l) |
| MTT | multiple trace theory |
| NCAM | neural cell adhesion molecule |
| NFκB | nuclear factor kappa-light-chain-enhancer of activated B cells |
| NfL | neurofilament light polypeptide/chain |
| NFT | neurofibrillary tangles |
| NgR1 | negative growth regulatory protein NGR1 |
| NMDAR | N-methyl-D-aspartate receptor, tetrameric protein with two GluN1 subunits and two GluN2 (A-D) subunits; a type of L-glutamate receptor |
| NPT2 | sodium-dependent phosphate transport protein 2A |
| NS | nucleation site |
| P-tau | phosphorylated tau protein |
| PET | positron emission tomography |
| PET SV2 | PET synaptic vesicle protein 2A tracer |
| PI3K | phosphoinositide 3-kinase |
| PirB | paired immunoglobulin-like receptor |
| PKA | protein kinase A |
| PKB | protein kinase B |
| PMN | parietal memory network |
| PSD-95 | postsynaptic density protein 95 (a postsynaptic scaffolding protein in excitatory neurons) |
| PSD(s) | postsynaptic density protein(s) |
| R-fMRI | resting state fMRI, evaluates intrinsic brain networks at rest by calculating correlations between brain regions |
| Rab | member of the Ras superfamily small G proteins |
| RAGE | receptor for advanced glycation end products, aka AGER |
| ROS | reactive oxygen species |
| SCI | subjective cognitive impairment |
| SCTs | standard consolidation theories |
| SEM | scanning electron microscopy |
| SMC | sensorimotor cortex |
| SNAP-25 | synaptosomal-associated protein 25 |
| SPECT | single-photon emission computerized tomography |
| SV2(A) | synaptic vesicle glycoprotein 2(A) |
| T-tau | total tau |
| TEM | transmission electron microscopy |
| TNFα | tumour necrosis factor α |
| VaD | vascular dementia |
| VDAC1 | voltage-dependent anion-selective channel 1 |