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. 2023 Jan 26;11(2):355. doi: 10.3390/biomedicines11020355
[11C]PiB (11)C-labeled Pittsburgh Compound-B
[11C]UCBJ (4R)-1-[(3-(11C)Methylpyridin-4-yl)methyl]-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one
[18F] fluorine radioisotope
[18F]FDG [18F]Fluorodeoxyglucose
[18F]MNI-1126 18F analog of [11C]UCB-J PET radioligand
[18F]SDM-16 (4R)-4-(3-fluoro-5-(fluoro-18F)phenyl)-1-((2-methyl-1H-imidazol-1-yl)methyl)pyrrolidin-2-one
[18F]SDM-16 (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one (UIPAC name)
[18F]SDM-8 (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one
[18F]SynVesT-1 (4R)-4-(3-(18F)fluoranyl-5-fluorophenyl)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-one
[18F]UCB-H (4R)-1-((3-Fluoranyl-4-pyridyl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one
99-CTF 99-amino acid membrane bound C-terminal fragment
99-CTF 99-amino acid membrane-bound C-terminal fragment
amyloid β
AβF amyloid β fibril
AβPF amyloid β protofibril
AD Alzheimer’s disease
ADHD attention deficit hyperactivity disorder
aMCI amnestic mild cognitive impairment
AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
AMPAR α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
APOE3 apolipoprotein E3
APOE4 apolipoprotein E4
APP amyloid-β precursor protein
APP amyloid precursor protein
APP669–711 amyloid-β precursor protein isoforms
ATN (amyloidβ (A), phosphorylated tau (T) and neurodegeneration (N) markers)
ATP adenosine triphosphate
AβO(s) amyloid β oligomer(s)
BDNF brain-derived neurotrophic factor
BOLD blood oxygenation level-dependent
bvFTD behavioural variant of frontotemporal dementia
CA1 hippocampal subfield/region CA1
CaMKII Ca2+/calmodulin-dependent protein kinase II
cdk5 cyclin-dependent kinase 5
CJD Creutzfeldt–Jakob disease
CREB cAMP response element-binding protein
CSF cerebrospinal fluid
DAB1 DAB adaptor protein 1
DAB1-P phosphorylated DAB adaptor protein 1
DMN default mode network
DNA deoxyribonucleic acid
DTI diffusion tensor imaging
EEG electroencephalogram
EM electron microscopy
EMG electromyography
EphB2 ephrin type-B receptor 2
FAD familial Alzheimer’s disease
FDG-PET fluorine-18 fluorodeoxyglucose PET imaging
fMRI functional magnetic resonance imaging
FYN proto-oncogene tyrosine-protein kinase Fyn
GABA gamma-aminobutyric acid
GABAB gamma-aminobutyric acid B receptor
GAP-43 growth-associated protein 43
GluA2 ligand-gated ion channel glutamate receptor
GluCEST glutamate chemical exchange saturation transfer
GluN1 NMDA receptor subunit GluN1
GluN2B NMDA receptor subunit GluN2B
GSK3β glycogen synthase kinase-3β
HT histochemical techniques
IDE insulin-degrading enzyme
IFITM interferon-induced transmembrane protein
IHC immunohistochemistry
IHT immunohistochemical techniques
LilrB2 leukocyte immunoglobulin-like receptor subfamily B member 2
LOAD late-onset form
LTD long-term depression
LTP long-term potentiation
M1 microglia microglia releasing inflammatory mediators, promotes inflammation and neurotoxicity
M2 microglia microglia releasing anti-inflammatory mediators, has an anti-inflammatory and neuroprotective effect.
MCI mild cognitive impairment
MEG magnetoencephalography
mGluR5 metabotropic glutamate receptor 5
miRs microRNAs
MMT memory manifold theory
MMT memory manifold theory
MRS MR spectroscopy
MT mitochondria(l)
MTT multiple trace theory
NCAM neural cell adhesion molecule
NFκB nuclear factor kappa-light-chain-enhancer of activated B cells
NfL neurofilament light polypeptide/chain
NFT neurofibrillary tangles
NgR1 negative growth regulatory protein NGR1
NMDAR N-methyl-D-aspartate receptor, tetrameric protein with two GluN1 subunits and two GluN2 (A-D) subunits; a type of L-glutamate receptor
NPT2 sodium-dependent phosphate transport protein 2A
NS nucleation site
P-tau phosphorylated tau protein
PET positron emission tomography
PET SV2 PET synaptic vesicle protein 2A tracer
PI3K phosphoinositide 3-kinase
PirB paired immunoglobulin-like receptor
PKA protein kinase A
PKB protein kinase B
PMN parietal memory network
PSD-95 postsynaptic density protein 95 (a postsynaptic scaffolding protein in excitatory neurons)
PSD(s) postsynaptic density protein(s)
R-fMRI resting state fMRI, evaluates intrinsic brain networks at rest by calculating correlations between brain regions
Rab member of the Ras superfamily small G proteins
RAGE receptor for advanced glycation end products, aka AGER
ROS reactive oxygen species
SCI subjective cognitive impairment
SCTs standard consolidation theories
SEM scanning electron microscopy
SMC sensorimotor cortex
SNAP-25 synaptosomal-associated protein 25
SPECT single-photon emission computerized tomography
SV2(A) synaptic vesicle glycoprotein 2(A)
T-tau total tau
TEM transmission electron microscopy
TNFα tumour necrosis factor α
VaD vascular dementia
VDAC1 voltage-dependent anion-selective channel 1