Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 1;13(2):276. doi: 10.3390/biom13020276

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of repeated oxaliplatin administration on cholinergic fibres in the stomach. (A) Cholinergic fibres labelled with the vesicular acetylcholine transporter (VAChT) in wholemount preparations of myenteric ganglia at days 3, 7, and 14 following the injection of sterile water (sham) and oxaliplatin (oxal). Scale bar: 100 μm. (B) Group data showing the density of VAChT-IR fibres per 0.25 mm² area in wholemount preparations of the gastric corpus of sham- and oxal-treated mice. (C) Cholinergic fibres labelled with VAChT in cross-section preparations of the gastric corpus at day 14 following the injection of sterile water (sham) and oxaliplatin (oxal). Scale bar: 100 μm. (D) Group data showing the density of VAChT-IR fibres in cross-section preparations of the stomach of sham- and oxal-treated mice. Data are presented as the mean ± SEM. The number of animals is shown in parentheses. *** p < 0.001; * p < 0.05.

Effects of repeated oxaliplatin administration on cholinergic fibres in the stomach. (A) Cholinergic fibres labelled with the vesicular acetylcholine transporter (VAChT) in wholemount preparations of myenteric ganglia at days 3, 7, and 14 following the injection of sterile water (sham) and oxaliplatin (oxal). Scale bar: 100 μm. (B) Group data showing the density of VAChT-IR fibres per 0.25 mm² area in wholemount preparations of the gastric corpus of sham- and oxal-treated mice. (C) Cholinergic fibres labelled with VAChT in cross-section preparations of the gastric corpus at day 14 following the injection of sterile water (sham) and oxaliplatin (oxal). Scale bar: 100 μm. (D) Group data showing the density of VAChT-IR fibres in cross-section preparations of the stomach of sham- and oxal-treated mice. Data are presented as the mean ± SEM. The number of animals is shown in parentheses. *** p < 0.001; * p < 0.05.