Table 5.
Clinical correlations of the absolute AAb deviations from AIR in the group of patients suffering from ME/CFS without comorbid FM. (Spearman correlation coefficient r and p-value).
| Subject Characteristics | Autoantibodies | r | p | |
|---|---|---|---|---|
| SF-36 Scales Median (IQR) |
Bodily pain | Anti-KiM-05 AAb | +0.611 | 0.046 |
| Anti-ScM AAb | +0.752 | 0.008 | ||
| Anti-HMMP AAb | +0.795 | 0.003 | ||
| Physical component score | Anti-ItM-07 AAb | +0.724 | 0.012 | |
| Mental component score | No significant correlation was found | |||
| MFI Scales Median (IQR) |
General Fatigue | Anti-ItM-07 AAb | −0.659 | 0.027 |
| Anti-SPr-06 AAb | +0.697 | 0.017 | ||
| Mental Fatigue | No significant correlation was found | |||
| Physical Fatigue | No significant correlation was found | |||
| Reduced Activity | Anti-V-Ca-Channel AAb | −0.620 | 0.042 | |
| Anti-Ach-Re AAb | +0.623 | 0.041 | ||
| Reduced Motivation | Anti-β Endorphin AAb | +0.665 | 0.026 | |
| HADS | Depression subscale | Anti-GABA-Re AAb | −0.639 | 0.034 |
| Anxiety subscale | Anti-SPr-06 AAb | −0.639 | 0.034 | |
| Anti-Dopa-Re AAb | −0.762 | 0.006 | ||
| Anti-MBP AAb | 0.820 | 0.002 | ||
| DSQ-SF | Composite score of cognitive symptoms | No significant correlation was found | ||
| Illness duration | Anti-Dopa-Re AAb | −0.652 | 0.03 | |
| Anti-GFAP AAb | +0.668 | 0.025 | ||
| Anti-TG AAb | +0.728 | 0.011 | ||
| Age | Anti-Fc-IgG AAb | −0.741 | 0.009 | |
| Anti-GaM-02 AAb | −0.636 | 0.035 | ||
| Anti-HeS-08 AAb | −0.800 | 0.003 | ||
| BMI | No significant correlation was found | |||