Table 7.
Clinical correlations of the absolute AAb deviations from AIR in HC group. (Spearman correlation coefficient r and p-value).
| Subject Characteristics | Autoantibodies | r | p | |
|---|---|---|---|---|
| SF-36 Scales Median (IQR) |
Bodily pain | Anti-CoM AAb | +0.774 | 0.005 |
| Anti-μ-Opioid-Re AAb | −0.719 | 0.013 | ||
| Physical component score | Anti-CoM AAb | +0.636 | 0.035 | |
| Mental component score | Anti-Dopa-Re AAb | −0.637 | 0.035 | |
| Anti-GABA-Re AAb | −0.664 | 0.026 | ||
| MFI ScalesMedian (IQR) | General Fatigue | No significant correlation was found | ||
| Mental fatigue | Anti-CoM AAb | −0.647 | 0.031 | |
| Physical Fatigue | No significant correlation was found | |||
| Reduced Activity | Anti-Adr-D\C AAb | −0.644 | 0.033 | |
| Reduced Motivation | No significant correlation was found | |||
| HADS | Depression subscale | Anti-LuM-02 AAb | −0.617 | 0.043 |
| Anti-Adr-D\C AAb | −0.683 | 0.020 | ||
| Anxiety subscale | Anti-μ-Opioid-Re AAb | +0.817 | 0.002 | |
| Anti-Ach-Re AAb | +0.696 | 0.017 | ||
| Anti-Dopa-Re AAb | +0.646 | 0.032 | ||
| DSQ-SF | Composite score of cognitive symptoms | Anti-μ-Opioid-Re AAb | +0.861 | 0.001 |
| Age | Anti-Ins-Re AAb | −0.657 | 0.028 | |
| BMI | Anti-CoM AAb | −0.737 | 0.010 | |
| Anti-ItM-07 AAb | −0.618 | 0.043 | ||
| Anti-HeS-08 AAb | −0.706 | 0.015 | ||
| Anti-TG AAb | −0.679 | 0.022 | ||
| Anti-S100 AAb | +0.632 | 0.037 | ||