ATP	adenosine triphosphate
CI	complex I (NADH:ubiquinone oxidoreductase)
CII	complex II (succinate dehydrogenase)
CIII	complex III (cytochrome c oxidoreductase)
CIV	complex IV (cytochrome c oxidase)
CV	complex V (ATP synthase)
CPEO	chronic progressive external ophthalmoplegia
DddAtox	deaminase-like toxin
DdCBE	DddA-derived cytosine base editor
DNA	deoxyribonucleic acid
DSB	double-strand break
dsDNA	double-stranded DNA
ETC	electron transport chain
FusXTBE	FusX TALE Base Editor
IBM	inner boundary membrane
IMM	inner mitochondrial membrane
IMS	intermembrane space
iPSC	induced pluripotent stem cell
LHON	Leber Hereditary Optic Neuropathy
MD	mitochondrial disease
MELAS	mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes
MERRF	myoclonus epilepsy associated with ragged-red fibers
MIDD	maternally inherited diabetes and deafness
mito-CRISPR/Cas9	mitochondria-targeted clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9
MitoRE	mitochondria-targeted restriction endonuclease
mitoTALEN	mitochondria-targeted transcription activator-like effector nuclease
mitoZFN	mitochondria-targeted zinc finger nuclease
mRNA	messenger RNA
mtDNA	mitochondrial DNA
MTS	mitochondrial targeting sequence
NARP	neuropathy, ataxia and pigmentary retinopathy
NES	nuclear export signal
OMM	outer mitochondrial membrane
OXPHOS	oxidative phosphorylation
PACE	phage-assisted continuous evolution
PANCE	phage-assisted non-continuous evolution
PBMC	peripheral blood mononuclear cell
RET	reverse electron transfer
RNA	ribonucleic acid
ROS	reactive oxygen species
rRNA	ribosomal RNA
TALE	transcription activator-like effector
TALED	TALE-linked deaminase
TCA	tricarboxylic acid
tRNA	transfer RNA
UGI	uracil glycosylase inhibitor
ΔΨm	mitochondrial transmembrane potential