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Female 5xFAD mice display age-dependent spatial learning deficits in the acquisition training. Escape latencies of 3- (a), 7- (c), and 12-month-old mice (e). Swimming speed did not differ between 5xFAD and WT mice at any age tested (b,d,f). Data presented as mean ± S.E.M., n = 10–13. Two-way repeated measures ANOVA: ### p < 0.001; Bonferroni: * p < 0.05, ** p < 0.01.
