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Male 5xFAD mice display age-dependent spatial learning deficits in the acquisition training. Escape latencies and swimming speed of 3- (a,b), 7- (c,d), and 12-month-old mice (e,f). Data presented as mean ± S.E.M., n = 10–13. Two-way repeated measures ANOVA: ## p < 0.01; ### p < 0.001; Bonferroni: * p < 0.05, ** p < 0.01, *** p < 0.001.
