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Cognitive scores of male 5xFAD mice. The cognitive scores of 5xFAD mice decreased age-dependently in the acquisition training (a,c,e) and the probe trial (b,d,f). Data presented as mean ± S.E.M., n = 10–13. Acquisition training: two-way repeated measures analysis of variance (ANOVA) followed by Bonferroni multiple comparisons. ANOVA: ## p < 0.01; Bonferroni: * p < 0.05, ** p < 0.01. Probe trial: unpaired t-test: * p < 0.05, ** p < 0.01.
